
1w3 min read
Medical Article
Introduction: The MANIFEST-2 trial is a pivotal phase 3 study evaluating the combination of pelabresib, a bromodomain and extraterminal domain (BET) inhibitor, with ruxolitinib, a Janus kinase (JAK) inhibitor, in patients with myelofibrosis who have not previously received JAK inhibitor therapy (1). Myelofibrosis is a progressive haematological mal

MANIFEST-2 Trial Supports Combination Therapy Benefit
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