CT-guided percutaneous transthoracic lung biopsy (CT-PTLB) is a minimally invasive procedure to acquire lung tissue. Pneumothorax, occurring in 18.8% to 45% of cases, is the most common complication, with a 3.1% to 20% chest drain insertion rate. Some institutions use pneumothorax aspiration to manage the condition and avoid chest drain insertion.
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