Congenital abnormalities(CAs) have a prevalence of about 14% of all human fetuses considering all types of abnormalities, that is, major (3%) and minor (11%), or lethal, severe, and benign. (1) Considering major CAs, congenital heart diseases account for almost 25%, limb defects for nearly 20%, and nervous system abnormalities for about 10%. (2) CA
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