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Medical Article
Introduction Gastrointestinal stromal tumors (GISTs) are the most common mesenchymal tumors of the gastrointestinal tract, arising predominantly from the interstitial cells of Cajal (ICC) (1–4). The majority of GISTs are driven by gain-of-function mutations in KIT or PDGFRA receptor tyrosine kinases, making them uniquely responsive to targeted ther

Gastrointestinal Stromal Tumors: Diagnosis, Staging, and Treatment
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