Introduction Oxidative stress represents a fundamental biological process linking aging with chronic disease (1). It occurs when reactive oxygen species overwhelm endogenous antioxidant defences, leading to cumulative cellular damage and accelerated functional decline. Smoking is a major source of exogenous oxidants, substantially increasing oxidat

Introduction The microvasculature plays a critical role in maintaining tissue perfusion, oxygen delivery, and metabolic homeostasis (1). Increasing evidence suggests that microvascular dysfunction is not confined to a single organ but represents a systemic pathological process influencing disease expression across cardiovascular, renal, neurologica

Can doctors trust artificial intelligence? Join our upcoming webinar to explore how clinicians can shape, validate, and guide AI tools that are transforming modern medicine. Hear from: Mr. Bharat Gera — AI in Healthcare: The Human Voice — Expectations, Fears, and What Works Dr. Annie Hartley — Clinician-Led AI: How Doctors Should Validate and Trust

Introduction Chronic low-grade systemic inflammation has emerged as a central biological mechanism linking cardiovascular, metabolic, renal, and respiratory diseases (1). Unlike acute inflammation, which is protective and self-limiting, chronic inflammation persists silently, progressively driving tissue damage and functional decline across organ s

As we transition into 2026, Medsynapse recognizes that the most significant advancements in healthcare are born from collective expertise. Medical progress is not merely an individual pursuit; it is a testament to the shared intellect, unwavering resilience, and profound professional advocacy that defines our community. Behind every clinical breakt

In this compelling KOL (Key Opinion Leader) interview, we sit down with Dr. Aakash Joshi, an accomplished Cardiothoracic and Vascular Surgeon from Ahmedabad, Gujarat, India, to explore how minimally invasive cardiac and vascular techniques are transforming modern heart care. Dr. Joshi highlights that minimally invasive cardiac surgery (MICS) is not

In this insightful KOL (Key Opinion Leader) interview, we sit down with Dr. Prerana Abhisheki, an experienced Cardiac Rehabilitation Specialist from Bengaluru, Karnataka, India, to explore the critical yet often underappreciated role of cardiac rehabilitation in cardiovascular care. Dr. Abhisheki emphasizes that cardiac rehab is not just post-treat

Introduction: Venous thromboembolism (VTE) remains a significant concern following orthopedic surgeries like total knee arthroplasty (TKA), affecting up to 40-60% of untreated patients despite prophylaxis (1). Current anticoagulants, such as low-molecular-weight heparin (e.g., enoxaparin), effectively reduce VTE but increase bleeding risks, particu

Introduction: Postoperative venous thromboembolism (VTE) remains a common and serious complication following major orthopedic procedures such as total knee arthroplasty (TKA). While conventional anticoagulants reduce VTE risk, their bleeding liability limits use in certain patient populations, especially those at increased hemorrhagic risk (1). Inh