Hello, and a warm welcome to MedX, where we bring you the latest news and insights from the world of medicine.  FDA Approves Diagnostic Test Guiding Targeted Endometrial Cancer Therapy The FDA has approved a new companion diagnostic test to identify patients with microsatellite-stable endometrial carcinoma who may benefit from combination immunothe

Introduction World Diabetes Day 2025, observed on 14 November, centres on the theme “Diabetes Across Life Stages.” The initiative recognises that diabetes care must evolve continuously—from childhood to adulthood and into senior years—to ensure not only glycaemic stability but also sustained physical, emotional, and social well-being across a patie

A 52-year-old man, previously diagnosed with diabetes, returns for review after evaluation revealed elevated cortisol and a 2.5 cm adrenal nodule suggestive of mild autonomous cortisol secretion. Despite therapy with metformin and a GLP-1 receptor agonist, his glucose levels remain unstable, alternating between highs and unexplained lows. Blood pre

A 52-year-old man presents with newly diagnosed diabetes mellitus. His BMI is 31 kg/m², HbA1c 8.1%, and he reports fatigue and mild polyuria. He is initiated on metformin and lifestyle therapy. After three months, his fasting glucose continues to fluctuate widely between 90 mg/dL and 210 mg/dL despite consistent adherence. His blood pressure remain

Hello, and a warm welcome to MedX, where we bring you the latest news and insights from the world of medicine.  FDA Approval for Thymidine Kinase 2 Deficiency Treatment The FDA has approved doxecitine and doxribtimine, marking the first approved therapy for thymidine kinase 2 deficiency (TK2d) in adults and pediatric patients with symptom onset at

Introduction Type 2 diabetes mellitus (T2DM) in children and adolescents is a growing global concern, driven by increasing rates of obesity, insulin resistance (IR), and sedentary lifestyles (1). Although several therapies are available for adolescent patients remain limited, often resulting in suboptimal glycemic control and long-term risk of comp

Introduction Insulin-resistant diabetes associated with lipodystrophy presents significant treatment challenges due to impaired adipose tissue function and extreme insulin requirements (1). Conventional insulin regimens often fail to achieve optimal glycemic control, necessitating innovative approaches such as concentrated insulin delivery (1). Con

Hello, and a warm welcome to MedX, where we bring you the latest news and insights from the world of medicine.  FDA Approves First Rapid 1-Minute HIV Self-Test The FDA has approved the first 1-minute HIV self-test, marking a major step toward accessible and private HIV screening. Using just a drop of blood, individuals can obtain accurate results i

The richness of Diwali sweets is a clinical hazard for our diabetic patients. As the holiday concludes, brace yourself for the surge of uncontrolled hyperglycemia—this case highlights the immediate steps to manage metabolic crisis and prevent progression to DKA in the days following the indulgence.