Introduction Diabetes insipidus (DI) is a rare endocrine disorder marked by hypotonic polyuria, intense thirst, dehydration, and weight loss (1). Its symptoms often overlap with other causes of polyuria, complicating diagnosis (2). Traditional methods like the water deprivation test offer limited accuracy (~70%) and poor tolerance, especially in di

Introduction The cation calcium is crucial for neural transmission, enzyme activity, myocardial function, coagulation, and cellular processes. While most calcium is stored in bones as calcium phosphate, a small portion circulates in cells and extracellular fluids. Normal calcium levels range from 8.9 to 10.1 mg/dL, though variations occur based on

Case Presentation: Patient: 5-year-old child, raised as a boy. Chief Complaint: Respiratory distress. History: Born at home; posterior hypospadias repair at age 2 without karyotyping; early pubic hair development; family history of unexplained neonatal death. Examination: Hypertension (180/100 mmHg, >99th percentile). Ambiguous genitalia (Prader Sc

Hello, and a warm welcome to MedX, where we bring you the latest news and insights from the world of medicine. FDA Grants Accelerated Approval to Atrasentan for IgA Nephropathy The FDA has granted accelerated approval to atrasentan for adults with primary IgA nephropathy at risk of rapid progression. The Phase III ALIGN trial demonstrated that atra

Primary hyperparathyroidism (pHPT) is increasingly diagnosed due to routine serum calcium screening, leading to evolving management approaches. Recently, there has been a notable rise in the occurrence of diseases as a result of the implementation of regular serum calcium screening. Previously, diagnosis often followed complications such as kidney

Can Type 2 Diabetes really go into remission? In this powerful and thought-provoking interview, Dr. Ravi Shah, leading Endocrinologist and Founder of Dr. Ravi's Diabetes & Endocrinology Centre, Ahmedabad, shares breakthrough insights into the evolving landscape of diabetes remission. From lifestyle interventions and pharmacological advancements to

A 48-year-old woman presented with fatigue, nausea, vomiting, and over 20 pounds of weight loss over two months. Initial labs revealed elevated TSH at 34.34 mIU/L. She began levothyroxine (L-T4) therapy, leading to partial symptom resolution. Symptoms recurred within weeks. Further testing showed low cortisol and prolactin levels, with ACTH stimula

Practical Tips for Managing Prediabetes English: https://ksphealth.org/manage-prediabetes-naturally/ Hindi: https://ksphealth.org/prediabetes-ke-upay/ Tamil: https://ksphealth.org/manage-prediabetes-naturally-tamil/ Video: https://www.youtube.com/watch?v=Loil2Sl8v7c Other topics are in: YouTube: https://www.youtube.com/channel/UCOyrYdQb-Of8NI6X32SX

Cardiovascular diseases (CVDs) burden is mainly due to ischemic heart disease (nearly half) and cerebrovascular disease (over one-third), with the rest linked to hypertension, inflammation, and rheumatic heart disease (1). According to World Health Organization (WHO) projections, 75% of the global CVDs burden occurs in low & middle-income countries