In this insightful KOL (Key Opinion Leader) interview, we speak with Dr. Archan Sil, a distinguished expert in Pediatric Clinical Immunology & Rheumatology from West Bengal, to shed light on the often-misunderstood world of pediatric immunodeficiency. Children with weakened immune systems face unique and complex health challenges—from recurrent inf

A 16-year-old female with an eight-year history of chronic spontaneous urticaria (CSU) presented with acute episodes of generalized swelling, dizziness, and shortness of breath, initially suspected to be allergic in origin. Despite treatment with antihistamines and mast cell stabilizers, she experienced four episodes of anaphylaxis within eight day

A five-year-old female with a personal history of allergic asthma and a family history of autoimmune thyroid disease was referred to the Immunoallergology department due to recurrent pruritic skin eruptions. The lesions had persisted for over three years, appearing regularly without any identifiable physical or allergenic triggers. There was no his

Introduction Allergic rhinitis (AR) and chronic urticaria (CU) are common, immune-mediated conditions that significantly impair patients' quality of life and productivity. AR, affecting up to 40% of children and 30% of adults, presents with nasal congestion, sneezing, and rhinorrhea, and frequently coexists with asthma (1). CU, characterized by rec

Pediatric migraine (PM) is the most severe primary headache in children, leading to decreased quality of life (1). A migraine episode usually presents as a unilateral headache that worsens with physical exertion and is often accompanied by photophobia, phonophobia, nausea, vomiting, and cutaneous allodynia (1,2). Epidemiological studies show that 7

Respiratory syncytial virus (RSV) is one of the most common causes of acute lower respiratory infections in children globally and contributes significantly to severe respiratory disease in elderly persons (1). Each year, RSV causes an estimated 3.6 million hospitalizations and approximately 100,000 deaths in children under 5 years of age (1,2). App

A 40-year-old woman with a 10-year history of primary infertility and irregular menstrual cycles (23-29 days in length) with bilateral blocked tubes and one failed IVF attempt was referred to the fertility unit. Endocrine evaluation revealed a follicle-stimulating hormone (FSH) level of 10.82 IU/L, luteinizing hormone (LH) of 10.5 IU/L, estradiol o

Introduction: Migraine is a common and often debilitating neurological disorder that affects approximately 8% of children and adolescents worldwide, with increasing prevalence in post-pubertal females (1). Despite its significant impact on school performance, social functioning, and psychological well-being, treatment options for pediatric migraine

Introduction Sickle cell disease (SCD) is a hereditary hemoglobinopathy characterized by chronic hemolytic anemia and vaso-occlusion. Among its most serious complications is central nervous system [CNS] involvement, which manifests as overt strokes, silent cerebral infarcts (SCIs), and cognitive impairment. These neurological morbidities are highly