Introduction: Barrett’s esophagus (BE) is a premalignant condition characterized by replacement of the normal squamous epithelium of the distal esophagus with specialized columnar epithelium, most commonly because of chronic gastroesophageal reflux (1). BE increases the risk of developing Barrett’s esophageal adenocarcinoma (BEA), a malignancy that

Introduction: Barrett’s esophagus (BE) is a premalignant condition in which normal squamous epithelium of the distal esophagus is replaced by specialized intestinal-type columnar epithelium (1). It develops most commonly in the setting of chronic gastroesophageal reflux disease (GERD) and represents the principal precursor lesion for esophageal ade

Introduction: Barrett’s esophagus (BE) is a premalignant condition in which the normal squamous lining of the distal esophagus is replaced by columnar epithelium (1). It is the only known precursor to esophageal adenocarcinoma (EAC), a malignancy whose incidence has risen steadily over recent decades (1). Although BE provides an opportunity for ear

Introduction: Androgenetic Alopecia (AGA) is the most common cause of non-scarring hair loss in adults (1). It is characterized by a gradual and progressive reduction in hair density in a typical distribution pattern (1). In men, this usually involves recession of the frontal hairline and thinning over the vertex, while the occipital scalp is relat

As we transition into 2026, Medsynapse recognizes that the most significant advancements in healthcare are born from collective expertise. Medical progress is not merely an individual pursuit; it is a testament to the shared intellect, unwavering resilience, and profound professional advocacy that defines our community. Behind every clinical breakt

Introduction: Androgenetic alopecia (AGA) is the most common type of non‑scarring hair loss in men and women (1). It progresses through gradual hair follicle miniaturization and a shortened hair growth cycle (1). Men typically present with frontal hairline recession and vertex thinning (male pattern hair loss), while women show diffuse thinning ove

Introduction: Androgenetic alopecia (AGA) is a chronic, non-scarring form of hair loss that affects both men and women and is the most common type of alopecia seen in clinical practice (1). It develops due to progressive miniaturization of hair follicles and shortening of the hair growth cycle, resulting in gradual and patterned thinning (1). Early

Introduction: Primary Ovarian Insufficiency (POI) is characterized by loss of normal ovarian function before the age of 40 years, leading to irregular or absent menstruation, hypergonadotropic hypogonadism, infertility, and systemic complications related to estrogen deficiency (1). This case suggests that even in a patient diagnosed with POI, resid

Introduction: Premature Ovarian Insufficiency (POI) is a characterized by loss of ovarian activity before the age of 40 years and is associated with infertility and systemic complications related to estrogen deficiency (1). While the causes of POI vary, effective disease management is essential to reduce long-term health risks and improve quality o